| Date & Time | Game | Venue |
|---|---|---|
| Dec. 8 (Time TBA) | Wilmington Wildcats at Lexington Minutemen | Hayden Ice Facility |
| December 12, 2021 | (2) Newton North Tigers at (4) Lexington Minutemen | Hayden Ice Facility |
| December 18, 2021 | (4) Lexington Minutemen at (3) Watertown/Wayland Raiders | John A. Ryan Arena |
| December 19, 2021 | (6) Arlington Catholic Cougars at (2) Lexington Minutemen | Hayden Ice Facility |
| Dec. 28 Postponed | Concord-Carlisle Patriots at Lexington Minutemen
Battle road classic |
Hayden Ice Facility |
| December 31, 2021 | (4) Needham Rockets at (0) Lexington Minutemen | Hayden Ice Facility |
| Jan. 3 Postponed | Lexington Minutemen at Somerville Highlanders
Postponed: Make-Up TBA |
Veterans Memorial Rink |
| January 05, 2022 | (5) Whitman-Hanson Panthers at (4) Lexington Minutemen | Hayden Ice Facility |
| January 08, 2022 | (2) Lexington Minutemen at (4) Essex Tech Hawks | Essex Sports Center |
| January 12, 2022 | (2) Lowell Catholic Crusaders at (0) Lexington Minutemen | Hayden Ice Facility |
| January 14, 2022 | (2) Lexington Minutemen at (3) Brookline Warriors
Jr. Beanpot 1st Round |
Foxboro Sports Center |
| January 15, 2022 | (0) Newton North Tigers at (2) Lexington Minutemen
Jr. Beanpot Championship/Consolation |
Foxboro Sports Center |
| January 17, 2022 | (7) Lexington Minutemen at (4) Saugus Sachems | Kasabuski Arena |
| January 22, 2022 | (1) Lexington Minutemen at (2) North Middlesex Patriots | Wallace Civic Center |
| January 24, 2022 | (2) Lexington Minutemen at (5) Chelmsford Lions | Chelmsford Forum |
| Jan. 29 Postponed | Lexington Minutemen at Groton-Dunstable Crusaders
PPD from 1-29 |
Wallace Civic Center |
| February 01, 2022 | (4) Bedford Bucs at (1) Lexington Minutemen | Hayden Ice Facility |
| February 05, 2022 | (0) Lexington Minutemen at (8) Marlboro Panthers | Navin Arena |
| February 06, 2022 | (1) Lexington Minutemen at (1) Somerville Highlanders | Veterans Memorial Rink |
| February 07, 2022 | (1) Oliver Ames Tigers at (3) Lexington Minutemen | Hayden Ice Facility |
| February 12, 2022 | (1) Lexington Minutemen at (4) King Philip Warriors | Foxboro Sports Center |
| February 18, 2022 | (2) Lexington Minutemen at (4) Acton-Boxboro Revolution | Nashoba Valley Olympia |
| February 22, 2022 | (1) Lexington Minutemen at (3) Groton-Dunstable Crusaders | Wallace Civic Center |
