Commonwealth Athletic Conference
| Date & Time | Division | Game | Venue |
|---|---|---|---|
| February 20, 2021 | Boys | (2) Northeast Tech Golden Knights at (1) Greater Lowell/Nashoba Tech Vikings | Chelmsford Forum |
| February 20, 2021 | Boys | (3) Bishop Fenwick Crusaders at (0) Essex Tech Hawks | Essex Sports Center |
| February 18, 2021 | Boys | (1) Shawsheen Rams at (0) Essex Tech Hawks | Essex Sports Center |
| February 17, 2021 | Boys | (5) Northeast Tech Golden Knights at (2) Greater Lowell/Nashoba Tech Vikings | Chelmsford Forum |
| February 16, 2021 | Boys | (1) Shawsheen Rams at (4) Lowell Catholic Crusaders | Chelmsford Forum |
